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Many patients notice reduced swelling and immediate relief from facial or jaw pain after just one session

There have been efforts to overcome these problems by modifying the drugs in different ways to circumvent these hindrance such as (1) isolate human native enzymes to reduce allergy, (2) isolate enzyme isoforms with higher specificities and efficiencies, (3) pegylate the enzymes to reduce allergy and prolong the half-lives, and (4) design drug combinations protocols to enhance the efficacy of chemotherapy by drug synergy and minimizing resistance

For example, an IM injection in the deltoid could hit the radial nerve or artery if placed too low

However, current efforts in this field have encountered limited success 40,42

Comprehensive Reviews in Food Science and Food Safety